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Analysis Group 1 included 3212 participants with data on SHS, analysis Group 2 had 5499 participants with data on urine cotinine levels, and analysis Group 3 included 521 participants with a smoking history within the last month (Figure 1)

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Finally, by analyzing decision-making behaviors between the stimulated (ON) and non-stimulated (OFF) conditions in the previously identified archetypal space, we revealed that VTA DA neuron activation draws individual phenotypes towards the GO archetype (i.e., increased GO archetypal composition), while VTA DA neuron inhibition draws individuals away from GO (Fig

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